Moreover, in some instances the DNA-binding domain provides clues ... enough to detect them. Figure 4: Heat map representation of transcription factor expression in 32 human organs and tissues.
A multi-institutional team of investigators have developed a catalog of transcription factor binding sites that regulate gene ...
The transcription factor regulatory network in Pseudomonas aeruginosa is complex and involves multiple regulators that respond to various environmental signals and physiological cues by regulating ...
A typical footprinting experiment involves radioactive labeling of the DNA region of interest—usually a larger chunk of DNA suspected to contain one or more transcription factor binding sites.
Mediator is a common target of DNA-binding transcription factors (TFs) and also interacts with various Pre-Initiation Complex (PIC) factors. The PIC consists of TFIIA, TFIIB, TFIID, TFIIE, TFIIF, ...
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Study reveals how transcription factors navigate DNA architecture to shape cellular identityThe research, titled "Nucleosome fibre topology guides transcription factor binding to enhancers," is published in Nature and provides a powerful framework for exploring gene regulation mechanisms.
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