By tethering RNA polymerase with the coupling transcription factor NusG or its paralog or version, RfaH, which threads the ...

Role of RNA polymerase in gene transcription demonstrated Date: July 19, 2010 ... we can look at the dynamics of RNAP and simulate how it shifts from one structure to another structure," explains ...

The Pre-Initiation Complex (PIC), which consists of Mediator, TFIIA, TFIIB, TFIID, TFIIE, TFIIF, TFIIH, and RNA polymerase II (RNAPII), governs the expression of all protein-coding and most non-coding ...

Crystal structure reveals new details of nonstandard RNA transcription Date: August 22, 2017 Source: Penn State Summary: By capturing the crystal structure of RNA polymerase during a ...

Scientists have now visualized loops of DNA molecules and seen the three-dimensional structure of these loops. Active genes have to be copied from the DNA molecule into mRNA molecules that the cell ...

In their work published in a recent issue of Science, they utilized cryo-electron microscopy (cryo-EM) to describe the various biochemical and/or conformational states of the complex, providing ...

RNA Polymerase Structure Subunits. ... Transcription Facilitated by RNA Polymerase I and III. The promoter sequence associated with the synthesis of rRNA is 150 base pairs in length.

Previously, the structure of RNA polymerase II was determined by Roger Kornberg of Stanford University, with whom Dr. Takagi worked prior to coming to IU School of Medicine. Kornberg received the ...

Riboswitches can control transcription through signal integration. An RNA motif, commonly found in bacterial riboswitches and in various human and plant pathogens, known as yybP-ykoY, plays a ...

Genome-wide probing of intracellular SARS-CoV-2 RNA structure with DMS-MaPseq. (A) Schematic of the experimental protocol for probing viral RNA structures with DMS-MaPseq.