Hahn, S. Structure and mechanism of the RNA polymerase II transcription machinery. Nature Structural and Molecular Biology 11, 394–403 (2004) (link to article) ...

RNA polymerase in action. The three stages of transcription involve various functions of RNA polymerase that result in the synthesis of RNA: 1. Initiation begins when RNA polymerase wraps around the ...

By tethering RNA polymerase with the coupling transcription factor NusG or its paralog or version, RfaH, which threads the ...

Transcription Facilitated by RNA Polymerase I and III. The promoter sequence associated with the synthesis of rRNA is 150 base pairs in length. Two transcription factors, ...

RNA polymerase (RNAP or RNApol) is an enzyme that produces RNA. In cells, RNAP is needed for constructing RNA chains from DNA genes as templates, a process called transcription.

Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA. Within a few hundred milliseconds, the DNA double helix unwinds to form ...

A breakthrough assay is advancing how researchers observe gene expression in real time. Named QRIVTA (quantitative real-time ...

DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted upon by an enzyme called RNA polymerase. This is a molecular machine which ...

Every living cell must interpret its genetic code—a sequence of chemical letters that governs countless cellular functions. A ...

CleanScribe RNA Polymerase is a novel DNA-dependent RNA polymerase that catalyzes the in vitro transcription (IVT) of a recombinant gene regulated by the T7 promoter.

What am I looking at? This is a 3D rendering of an RNA polymerase II enzyme from baker’s yeast, created using actual molecular data to reconstruct its shape and active sites. What looks like a ...