Nature18d
A new dual-vector approach to enhance recombinant adeno-associated virus-mediated gene expression through intermolecular cis activation
Based on this, we have developed a new approach to enhance the efficiency of rAAV-mediated gene expression. This approach uses co-infection with a transgene-containing vector and a second vector ...
Nature26d
Competitive Inhibition of Mammalian Tyrosinase by Phenylalanine and its Relationship to Hair Pigmentation in Phenylketonuria
Three possible hypotheses may be advanced to explain the reduction of melanin formation: absence of the melanin-forming enzyme, tyrosinase; absence or decrease of the melanin precursor ...