In a study of newborn piglets, infection with influenza A was associated with disruptions in the piglets' nasal and gut microbiomes, and with potentially detrimental changes in gene activity in the ...

The COVID pandemic illustrated how urgently we need antiviral medications capable of treating coronavirus infections. To aid ...

In a study of human immune cells infected with HIV, the virus that causes AIDS, scientists at Johns Hopkins Medicine say a ...

New imaging tools reveal how within an hour of infection, the virus begins to alter our chromosomes to kick-start its own replication.

They identified two neighboring genes—an RNA-editing enzyme (old) and a transcription factor (zao)—that regulate virus-induced gene expression. Their findings show how the old-zao module controls both ...

The new finding indicates SARS-CoV-2 can disrupt our genes and their expression. DNA is coiled around histone proteins so it can be tightly packed in a cell nucleus. Wikimedia Commons , CC BY ...

Hepatitis B virus-induced hepatocellular carcinoma (HCC) remains a major global health burden, and new therapeutic and diagnostic approaches are ...

Investigating how mutations in tumors alter DNA’s 3D structure—and subsequently, regulatory sequences called enhancers—can ...

A new gene drive can copy and paste itself into the genomes of herpes simplex viruses in mice. The end goal is a version that disables the virus in humans.

Manipulating Gene Expression to Treat Disease. Several of our scientists study gene regulation in specific cancers, including cancers of the blood, lung, pancreas and prostate. They seek treatment ...

A study published in the journal Cell marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells.