In a study of newborn piglets, infection with influenza A was associated with disruptions in the piglets' nasal and gut microbiomes, and with potentially detrimental changes in gene activity in the ...

The COVID pandemic illustrated how urgently we need antiviral medications capable of treating coronavirus infections. To aid ...

New imaging tools reveal how within an hour of infection, the virus begins to alter our chromosomes to kick-start its own replication.

Professor Hirohide Saito (Department of Life Science Frontiers at CiRA / The University of Tokyo) and Assistant Professor ...

They identified two neighboring genes—an RNA-editing enzyme (old) and a transcription factor (zao)—that regulate virus-induced gene expression. Their findings show how the old-zao module controls both ...

The Johns Hopkins team that conducted the new study had previously shown that the molecule of interest, an “antisense ...

Hepatitis B virus-induced hepatocellular carcinoma (HCC) remains a major global health burden, and new therapeutic and diagnostic approaches are ...

bacteria virus gene expression antiviral In 1933, geneticist Thomas Hunt Morgan won the Nobel Prize in Physiology or Medicine for demonstrating that genes exist on chromosomes, which are passed ...

Investigating how mutations in tumors alter DNA’s 3D structure—and subsequently, regulatory sequences called enhancers—can ...

A new gene drive can copy and paste itself into the genomes of herpes simplex viruses in mice. The end goal is a version that disables the virus in humans.

Manipulating Gene Expression to Treat Disease. Several of our scientists study gene regulation in specific cancers, including cancers of the blood, lung, pancreas and prostate. They seek treatment ...