1a to 1c). We found that that the DNA Polymerase III holoenzyme, which is the replicative DNA polymerase in the replisome, (prepared from a strain deleted of the genes for all the TLS polymerases and ...

DNA polymerases carry out crucial functions in many DNA metabolic processes. Polymerases catalyse the addition, using a template, of complementary nucleotides to the 3′ end of DNA primer strands.

radiodurans polA mutants, which encode the Pol I polymerase, show substantial defects in synthesis and repair following irradiation. Determining whether such a role for Pol III exists during DNA ...