How were these viruses using the cell's endocytic pathway? The first step for a virus to invade a cell is to cross the cell's plasma membrane, which is a lipid barrier. In general, a virus ...

Higher organisms have evolved a plethora of endocytic pathways with unique characteristics. Nonetheless, one common feature of all types of endocytosis is the use of actin-generated forces to aid ...

It is well established that, in many instances, ligand binding to a receptor triggers the internalization of the receptor–ligand complex and its transport through the endocytic pathway towards ...

1. Chaperone-assisted Adaptor Protein Assembly (CAPA). Our group discovered the CAPA pathway while identifying endocytic regulators. Adaptor proteins (APs) are heterotetrameric complexes that function ...