Mediator is a common target of DNA-binding transcription factors (TFs) and also interacts with various Pre-Initiation Complex (PIC) factors. The PIC consists of TFIIA, TFIIB, TFIID, TFIIE, TFIIF, ...

Although one type of location-based test (ChIP-qPCR ... team are now exploring how this mechanism operates in other transcription factor families, as well as in species beyond the model used ...

If DNA is a book, then how is it read? Learn more about the DNA transcription process, where DNA is converted to RNA, a more portable set of instructions for the cell. The process of transcription ...

The transcription factor CDX2—which plays an important ... More information: Lijing Yang et al, Tissue-location-specific transcription programs drive tumor dependencies in colon cancer, Nature ...

It seems that the ATPase binds approximately 40 base pairs inside the nucleosome, from which location it pumps ... act as a physical barrier to transcription factors that need to bind to certain ...