Research studies in cardiovascular epidemiology assessing the relationship between a primary exposure and a health outcome must account for the presence of what are often called third variables, ...

Acute fulminant myocarditis (AFM) is characterized by sudden, severe cardiac inflammation causing hemodynamic instability or arrhythmia. 1 Currently, no approved medical therapy exists for AFM. Janus ...

BACKGROUND: Evaluation of whether dyspnea has a cardiac cause is essential. Guidelines from 2016 were reported to result in a high incidence of indeterminate left ventricular (LV) filling pressure. We ...

Figure. Scientific questions that can be addressed using the Cardiovascular Disease Knowledge Portal. A, The phenotype page, illustrated for the atrial fibrillation (AF) phenotype, illuminates the ...

The surgical procedure was completed successfully. Pulsed field energy can travel through the fatty tissue to form a lesion in the cardiomyocytes (Figure [D and E]).The mean depth of the lesion in the ...

In this issue, Glotzbach et al 11 report the heritability and risk estimates of BAV, TAA, and aortic dissection in a large population-based study of almost 4 million individuals in the Utah Population ...

Results: Between 1999 and 2020, 14,309,991 cancer-related deaths occurred in the US out of which 612,346 were associated with cancer and heart failure. The overall AAMR per 100,000 for cancer-related ...

Background: The voltage-gated potassium ion channel KV11.1 plays a crucial role in cardiac repolarization. Genetic variants in KV11.1 lead to Long QT Syndrome (LQTS), a condition associated with fatal ...

Background: Coronary heart disease (CHD) remains the primary cause of mortality and morbidity in the USA. Although rodents are widely used to explore mechanisms, they have major biological differences ...

BACKGROUND: The American Heart Association (AHA), in conjunction with the National Institutes of Health, annually reports the most up-to-date statistics related to heart disease, stroke, and ...

BACKGROUND: Penetrance and risk of ventricular arrhythmias (VAs) in arrhythmogenic right ventricular cardiomyopathy (ARVC) are increasingly recognized as being genotype specific. Therefore, ...