The binding potential of albumin as well as total bilirubin concentrations can vary substantially between infants and according to postnatal age (days) during a treatment period with ibuprofen.

Albumin is the most abundant protein in human serum. Its major function is to exert osmotic pressure, but it also has ligand binding, antioxidant and endothelial stabilizing properties The use of ...

Combined company expected to become largest U.S.-based publicly listed company to hold HYPE in its treasuryPRINCETON, N.J., July 14, 2025 ( ...

To boost mood and manliness, men are spending lots of money on the hormone testosterone—yet they may see trouble instead of ...

But, by connecting the STING agonist to the albumin-binding nanobody, researchers were able to strongly improve its antitumor effects.

PD-L1 is the target of several clinically approved cancer immunotherapies. By linking the STING agonist to this bivalent nanobody – with one end binding to albumin and the other to PD-L1 – they found ...

Peptides have emerged as a fascinating area of scientific inquiry due to their potential to modulate various physiological ...

SNMMI annual meeting featured a radiotheranostics session and a presentation by Dr. Xuejen Wen discussing the development of PSMA targeting radioligand 161 Tb-LNC1011 for prostate cancer theranostics.

Nanoparticles (NPs) are materials whose dimensions range from 1 to 1,000 nanometers (nm). Due to their nano-scale dimensions and tunable material properties, NPs have gained interest in the global ...

ACROBiosystems has developed a series of specialized proteases for the screening and validation of ADC linkers, focusing on ...

Albumin is the most abundant protein in human serum and drugs that are administered intravenously inevitably interact with it. We present here a series of platinum(IV) prodrugs designed specifically ...

Biogenic polyamines are found to modulate protein synthesis at different levels, while polyamine analogues have shown major antitumor activity in multiple experimental models, including breast cancer.