Researchers analyzed 45,766 cells and identified 66 distinct transcriptomic neuron types (t-types). Based on differential gene expression , these t-types were further categorized into 33 ...

iAssembloids combine hiPSC-derived neurons, microglia, and astrocytes in 3D spheres. CRISPRi screening revealed genes that affect neuron survival in iAssembloids but not in 2D monoculture. One gene, ...

This study demonstrates the critical role of Afadin on the generation and maintenance of complex cellular layers in the mouse retina. The data are solid, which provides important insights into how ...

The Food Safety Information Council has issued food safety advice for consumers about how to be prepared for power outages. Dr. Scott Crerar, Council Chair, said that the Council has been ...

The purpose of this study was to examine the differences in the epidemiology and histologic distribution of NSCLC in smokers with NSCLC compared to never-smokers with NSCLC. We also wanted to ...

In particular, we offer detailed explanations and hypotheses regarding the concerted regulation of purinergic signaling and circadian oscillations by neurons and astrocytes, and review the diverse ...

This important study identifies a new key factor in orchestrating the process of glial wrapping of axons in Drosophila wandering larvae. The evidence supporting the claims of the authors is convincing ...

However, changes of ephrin-B1 levels in astrocytes did not affect spine enlargement, as no genotype differences in spine volume were observed between trained WT, KO, and OE groups. Our results suggest ...

1 Biomedical Center Munich (BMC), Physiological Genomics, LMU Munich, 82152 Planegg-Martinsried, Germany. 2 Institute of Stem Cell Research, Helmholtz Center Munich, BMC LMU Munich, 82152 ...

Frozen section histology provides rapid results using unfixed tissue for techniques such as fat demonstration, immunohistochemistry, immunofluorescence and enzyme histochemistry. Most routine ...