Autophagy and apoptosis may be triggered by ... The second pathway involves the conjugation of phosphatidylethanolamine (PE) to LC3/Atg8 (LC3 is one of the mammalian homologues of Atg8) by the ...
Initially it was thought that the main role of TBK1 during selective autophagy was facilitating the interaction between ATG8 family protein members and the selective cargo via selective autophagy ...
The generation of PI3P facilitates the recruitment of autophagy-related machinery, including the ATG16L1-ATG5-ATG12 complex, ATG3, and ATG7. These components work synergistically to conjugate ATG8 ...
In flies defective for axonal transport of mitochondria, the authors report the upregulation of one subunit, the beta subunit, of the heterotrimeric eIF2 complex via mass spectroscopy proteome ...
1Cellular Degradation Biology Center, College of Medicine, Seoul National University, Seoul, Republic of Korea. 2Department of Biomedical Sciences, College of Medicine, Seoul National University, ...
This important study investigates the role of ATG6 in regulating NPR1, a key protein in the plant immune response. The authors present compelling evidence that ATG6 not only interacts with NPR1 in ...
Henan Key Laboratory of Environmental and Animal Product Safety, College of Animal Science and Technology, Henan University of Science and Technology, Luoyang 471000, Henan,China ...
Department of Chemical Sciences, Tata Institute of Fundamental Research, Mumbai 400005, India ...
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