X-linked myopathy with excessive autophagy (XMEA) is a rare disease for which pre-clinical models lack, challenging the ...

Key Laboratory of Functional Polymer Materials of Ministry of Education, State Key Laboratory of Medicinal Chemical Biology, Institute of Polymer Chemistry and College of Chemistry, Nankai University, ...

One of their survival strategies is autophagy, a process in which cells degrade and recycle waste products. This mechanism not only allows cancer cells to expel anticancer drugs but also provides ...

The SGLT2 inhibitor empagliflozin alleviated podocyte injury by attenuating inflammation and enhanced autophagy by reducing mTORC1 activity ... Proteintech); images were visualised using a FluorChem R ...

The evidence supporting the claims of the authors is solid. However, the observed changes in autophagy are moderate, the images were not fully represented by the quantification results, and some of ...

What will you work on in AUTORHYTHM? In AUTORHYTHM, my work will focus on developing and applying artificial intelligence tools to assist biologists in analyzing autophagy imaging data. Additionally, ...

Autophagy is an evolutionarily conserved mechanism of cell ... autophagic-driven mitochondria release from cardiomyocytes to MerTK + macrophages. Advanced imaging techniques including light sheet ...

Here, we evaluated two commonly used fluorescence-based imaging methods to detect mitophagy in ESCs. By using autophagy- or mitophagy-defective ESC lines, we showed that the mito-Keima (mt-Keima) ...

This month's cover highlights the article DNA damage response at telomeres boosts the transcription of SARS‐CoV‐2 receptor ACE2 during aging by Sara Sepe, Francesca Rossiello, Fabrizio d’Adda di ...

Researchers from the Tokyo Medical and Dental University (Tokyo, Japan) have published a study in Autophagy revealing a new technique to live image ubiquitin tail formation by genetically engineering ...