Nature9d
Autophagy: from phenomenology to molecular understanding in less than a decade
The overall morphology is identical to nonspecific autophagy; however, the sequestering Cvt vesicles are smaller than autophagosomes and they appear to exclude bulk cytoplasm. The phagophore ...
Nature12y
The Discovery of Lysosomes and Autophagy
What do cells do when they are “hungry”? Eukaryotic cells cope with starving conditions by eating their own components, a process called autophagy. Aa Aa Aa Normally, when you are hungry you ...
EurekAlert!2y
Figure 2: Studying Autophagy with Fluorescence Resonance Energy Transfer (IMAGE)
In the experiment, Cy3 is attached to CB[7] and Cy5 to AdA. During autophagy, the two dyes come closer and Cy3 transfers some energy to its nearby partner dye Cy5, following the FRET phenomenon.
Phys.org28d
CaMKIIβ key in transducing Ca²⁺ transients to initiate autophagosome formation: Study
Transient Ca 2+ fluctuations on the surface of the endoplasmic reticulum (ER) can induce liquid-liquid phase separation (LLPS) of the autophagy initiation complex FIP200, forming FIP200 puncta and ...