Schmid and colleagues 1 reveal that genetic enhancement of mitophagy via neuronal overexpression of BNIP3 alleviates brain aging and prolongs healthspan in fruit flies. Mitochondrial fission in ...

Additional validation in larger cohorts is necessary. Second, sufficient clinical samples must be used to verify the prediction accuracy of the three most important genes (BNIP3, N6AMT1, and ICOS).

Ischemic stroke is a major cause of mortality and disability worldwide. Among patients with ischemic stroke, the primary treatment goal is to reduce acute cerebral ischemic injury and limit the ...

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