Method: This study is a post-hoc analysis of the PLATELET trial (A Multicenter Prospective Observational Study to Evaluate the Effect of Clopidogrel on the Prevention of Major Vascular Events ...

Metoprolol is used for phenotyping of cytochrome P450 (CYP) 2D6, a CYP isoform considered not to be inducible by inducers of the CYP2C, CYP2B, and CYP3A families such as rifampicin. While assessing ...

A growing body of evidence links use of proton pump inhibitors to kidney problems, including kidney failure in patients with existing CKD.

A member of cytochrome P450 family, CYP39A1, was one of the top liver-specific candidates with significantly higher levels in female vs male liver. In HCC tumours, CYP39A1 expression was dramatically ...

CYP51 (Erg11) belongs to the cytochrome P450 monooxygenase (CYP) superfamily and mediates a crucial step of the synthesis of ergosterol, which is a fungal-specific sterol. It is also the target of ...

The FDA has approved Journavx 50 mg oral tablets for the treatment of moderate to severe acute pain in adults, according to a ...

The same study also found that taurine reduced the resistance of blood flow in the blood vessel walls and enhanced the ...

School of Traditional Chinese Medicine, Capital Medical University, Beijing 100069, China ...

State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China University of Chinese Academy of Sciences, Beijing 100049, China State Key ...

Statins and vitamin D are also metabolized (broken down) by the same liver enzyme, cytochrome P450 3A4 (CYP3A4). If you take both vitamin D and a statin, they will compete for the enzyme.