A recent study published in Genes & Diseases reveals a novel role of XPR1 in promoting ovarian cancer growth by regulating ...

Researchers at Leipzig University's Carl Ludwig Institute have discovered that in the cerebral cortex, synaptic signal ...

A recent review by Prof. Zhu Bing and Associate Professor Xiong Jun from the Institute of Biophysics of the Chinese Academy ...

R136S, or the “Christchurch mutation,” appears to protect against Alzheimer’s disease by suppressing inflammatory signaling ...

PRESS RELEASE NEW PEER-REVIEWED DATA PROVIDE STRONG EVIDENCE SUPPORTING MASITINIB'S POTENTIAL FOR THE TREATM ...

Furthermore, the mechanistic investigations indicated that d-RuO 2 attenuated the progression of OA by suppressing the ROS/NLRP3/Caspase-1 signaling pathway. In conclusion, we presented d-RuO 2 as an ...

We show that this caspase-dependent disruption of cytokeratin is activated by cytoplasmic RNA recognition pathway. In addition, we show that viral infection activates 14-3-3 protein mediated signaling ...

They find that the cells of the wing pouch are more likely to have non-autonomous caspase activation than other regions within the wing imaginal disc (hinge and notum),two signaling pathways that are ...

Apoptosis is a physiologically crucial process for the control of cellular development and homeostasis in multi-cellular organisms. It occurs as a result of signal cascades in a complex cellular ...

Results: The oral adiponectin receptor agonist, AdipoRon, inhibited HFpEF inflammation by downregulating NLRP3, caspase-1, IL-1β and IL-18, and suppressing the TLR4/NF-κB/TNF-α signaling pathway. This ...

The inflammatory factors IL-1β, IL-18, CRP and ROS were significantly elevated (P β, IL-18, CRP, ROS and the expression of ASC, Nlrp3, Caspase-1, and GSDMD mRNA were significantly elevated (P ...