However, a greater quantity of GluR1 in the cell did not increase the quantities of receptors on the cell membrane or in synapses. Yet this was the case for GluR2.

Based on meta-analysis of over 100 studies of transmembrane cell-surface receptors, experts have proposed a new model for receptor activation -- the "rotation model." If the model proves correct ...

Study identifies proximity-based mechanism behind LAG-3 inhibition and introduces novel bispecific antibody for autoimmune ...

Prof. De Meyts assures that "Prof. Maruyama makes a convincing case that this [dimerization] model is incorrect, and that in fact, numerous cell membrane receptors are pre-dimerized in the ...

Nearly 70% of the drugs currently being developed target membrane receptors. Located outside the cell, these receptors play a decisive role in transmitting information to the inside of the cell.

Special molecules called T cell receptors (TCRs) sit on the cell membrane, where they receive messages from other cells. You can imagine TCRs as fire-spotters, the lookouts who scan for smoke from ...

Nature Medicine - Cell membrane estrogen receptors resurface. Collins, P. & Webb, C. Estrogen hits the surface. Nature Med. 5, 1130–1131 (1999). Article CAS Google Scholar ...

Taste, pain, or response to stress—nearly all essential functions in the human body are regulated by molecular switches called G protein-coupled receptors (GPCRs). Researchers at the University ...