However, a greater quantity of GluR1 in the cell did not increase the quantities of receptors on the cell membrane or in synapses. Yet this was the case for GluR2.

Study identifies proximity-based mechanism behind LAG-3 inhibition and introduces novel bispecific antibody for autoimmune ...

Based on meta-analysis of over 100 studies of transmembrane cell-surface receptors, experts have proposed a new model for receptor activation -- the "rotation model." If the model proves correct ...

Taste, pain, or response to stress—nearly all essential functions in the human body are regulated by molecular switches called G protein-coupled receptors (GPCRs). Researchers at the University ...

Nature Medicine - Cell membrane estrogen receptors resurface. Collins, P. & Webb, C. Estrogen hits the surface. Nature Med. 5, 1130–1131 (1999). Article CAS Google Scholar ...

Special molecules called T cell receptors (TCRs) sit on the cell membrane, where they receive messages from other cells. You can imagine TCRs as fire-spotters, the lookouts who scan for smoke from ...

Data from the Web of Science (ISI, Philadelphia) show that Hot Papers are cited 50 to 100 times more often than the average paper of the same type and age. M. Razandi, A. Pedram, G.L. Greene, E.R.

Drug discovery can be a long and complex process. Medicines for neurodegenerative diseases like Alzheimer's disease are among ...

Engineered cell therapies rely on synthetic receptors to transduce external signals into intracellular responses. The precise ...