Long-term, persistent weekly or more frequent cannabis smoking leaves a distinct and partially reversible epigenetic ...

The addition of a methyl group to the fifth carbon on cytosine (forming 5-methylcytosine or 5mC) alters how the surrounding DNA interacts with transcriptional effectors, often decreasing its ...

We evaluated whether 5hmC signatures in cell-free DNA (cfDNA) are associated with treatment failure to androgen-deprivation therapies (ADT) among men with hormone-naive prostate cancer. We collected a ...

The DNA was then treated with the enzyme methyltransferase, which recognizes the methylated cytosine and copies the methylation information to the DNA template.

Epigenetics involves a series of biological processes that regulate chromatin-mediated DNA templates. 2 Cancer is a ...

Two years later, Horvath demonstrated that cytosine methylation enables the creation of a mathematical model for estimating age across all human tissues.

DNA methylation refers to the process of adding a methyl group to one of the bases of your DNA. We’ll explore how this process effects gene expression and why experts believe it could be the key ...

Through these experiments, researchers synthesized thymine, cytosine and the other primary nucleobases, suggesting that all of these compounds could theoretically be detectable in meteorites, the ...

DNA methylation has an intrinsic effect on 3D genome structure. / Credit: IRB Barcelona Reporting in Nature Communications, researchers used yeast cells to show that methyl groups can increase the ...

These investigators performed the first epigenome-wide prospective meta-analysis to identify DNA methylation sites associated with pediatric ADHD symptoms.