Backgroud: Ferroptosis is a form ... including expansion of the endoplasmic reticulum (ER), mitochondrial shrinkage, and other morphological changes. Inositol requiring enzyme 1 (IRE1) a proximal ER ...
Figure 1 Sensing and responding to endoplasmic reticulum stress: canonical roles of unfolded protein response. In response to an increasingly accumulation of misfolded proteins in endoplasmic ...
Objective Investigating the effect of ferroptosis in the tumour microenvironment to identify combinatory therapy for liver cancer treatment. Design Glutathione peroxidase 4 (GPx4), which is considered ...
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