While it is accepted that extracellular vesicles (EVs)-mediated transfer of microRNAs contributes to intercellular communication, the knowledge about molecular mechanisms controlling the selective and ...

Transcriptional regulatory elements are nucleotide sequences of a gene that are involved in regulation of genetic transcription. These include the promoter, plus response elements, activator and ...

“If one gene showed parent-specific expression, another gene in the same pathway showed parent-specific expression from the opposite parent.” Previously, the team examined whether DNA methylation – a ...

Despite spanning about three billion base pairs, the human genome is wrapped up tight in a highly organized fashion in the nucleus. This coordinated structure, in part, enables the cell to regulate ...

Selective targeting of genome amplifications and repeat elements by CRISPR-Cas9 nickases to promote cancer cell death Focal gene amplification is a common feature of advanced and metastatic cancers.