Nature4d
A new dual-vector approach to enhance recombinant adeno-associated virus-mediated gene expression through intermolecular cis activation
Using this cis-activation strategy in primary ... we constructed several rAAV vectors with defined regulatory elements and/or the luciferase reporter gene (Fig. 1). AV.Luc contains only the ...
Frontiers4d
New Era of Studying RNA Secondary Structure and Its Influence on Gene Regulation in Plants
The dynamic structure of RNA plays a central role in post-transcriptional regulation of gene expression such as RNA maturation, degradation, and translation. With the rise of next-generation ...
GitHub4d
Center for Eukaryotic Gene Regulation
The CEGR is composed of Cornell laboratories focused on understanding the mechanisms of gene regulation.
Frontiers4d
Structures and Functions of the 3′ Untranslated Regions of Positive-Sense Single-Stranded RNA Viruses Infecting Humans and Animals
which blocks the recruitment of ribosomes to the IRES element. At this time, RdRP 3D can successfully pass through the RNA and synthesize negative-strand RNA from 3′ to 5′ (Perera et al., 2007).