Severe eosinophilic is effectively treated with benralizumab, with especially good outcomes in patients with high BEC and high FeNO.

Asthma is one of the major growth areas in therapeutics and many new drugs are currently in development. These drugs include improvements of existing classes of drugs, notably once-daily inhaled ...

There was overlap between the group with poor asthma control and the eosinophilic subtype, with all but one of the eosinophilic subjects having poor asthma control, and so in this study it is perhaps ...

Chronic eosinophilic inflammation is associated with tissue remodeling and fibrosis in a number of chronic T-helper 2 (Th2)-mediated diseases including eosinophilic esophagitis (EoE) and asthma.

ccdhb.org.nz Methods We included peer-reviewed publications of randomised controlled trials (RCTs) that enrolled children or adults in any healthcare setting and compared epinephrine by any route to ...

Apart from playing critical roles in the initiation of allergic reactions such as asthma, eosinophils are also effector cells in the induction of non-IgE mediated inflammation such as eosinophilic ...

the drug could also face strong competition from AstraZeneca’s AZN Fasenra, also an IL-5 inhibitor. This AZN drug is currently approved for two indications, namely eosinophilic asthma and EGPA.

00001) as well. However, the researchers said, there were no significant differences in cAMP levels between patients with eosinophilic asthma, defined as 300 cells/µL or higher, or neutrophilic ...