While surgery using 5-aminolevulinic acid improves total resection rates in high-grade glioma, the best outcomes are seen ...

Announcing a new article publication for BIO Integration journal. Liver fibrosis is caused by excessive extracellular matrix accumulation, which in turn is driven by activation of hepatic stellate ...

This valuable study presents a novel approach to enhance the therapeutic potential of mesenchymal stromal cells (MSCs) by genetically modifying their glycogen synthesis pathway, resulting in increased ...

Glioma tumor cells have changes in one or more genes that help the cells divide and spread. Different gliomas may have changes in different genes, such as the BRAF, IDH1, or IDH2 genes.

Key Takeaways The FDA's breakthrough therapy designation accelerates the development of B7-H3 targeting CAR-T cell therapy for pediatric diffuse intrinsic pontine glioma (DIPG). Promising phase 1 ...

Treatment strategy reprograms brain cancer cells, halting tumor growth Researchers combine radiation with a plant-derived compound to combat glioblastoma Date: February 26, 2025 Source: University ...

Back in December 2015, when we were still working on proving this, I was invited to speak at [Heidelberg University in Germany] by Frank Winkler, who had just discovered that glioma cells connect ...

What’s New An AI-based diagnostic system reveals cancerous tissue that may not otherwise be visible during brain tumor surgery. This enables neurosurgeons to remove it while the patient is still under ...

Key Takeaways CLD-101, a stem cell-based platform, delivers oncolytic viruses to tumors, targeting high-grade glioma in a phase 1b/2 trial. Previous trials demonstrated CLD-101's safety and potential ...

See the article: Chen Z, Gao Q, Shang Y, et al. HiTIP-seq profiles epigenomic reprogramming of patient-derived diffuse midline glioma stem cells to epigenetic therapy. hLife.

Diffuse midline glioma (DMG) is an incurable malignancy with the highest mortality rate among pediatric brain tumors. While radiotherapy and chemotherapy are the most common treatments, these ...

Background: Gaseous hydrogen sulfide (H 2 S), a by-product of cysteine metabolism, inhibits the growth of glioblastoma (GBM) cells and impairs GBM progression in mice. Likewise, H 2 S generation and ...