Unlike N-glycosylation, no sites of O-glycosylation of APP have previously been reported. We report here the identification of three specific O-glycosylation sites of the secreted APP695 (sAPP695) ...

More information: Shin-ichiro Yoshimura et al, Oxr1 and Ncoa7 regulate V-ATPase to achieve optimal pH for glycosylation within the Golgi apparatus and trans-Golgi network, Proceedings of the ...

Fig. 1 Illustrated model for the mechanism of luminal pH control in the Golgi/TGN via Oxr1 and Ncoa7., CC BY, 2025, Shin-ichiro Yoshimura et al., Oxr1 and Ncoa7 regulate V-ATPase to achieve optimal pH ...

Northwestern University biophysicists have developed a new computational tool for identifying the gene combinations underlying complex illnesses like diabetes, cancer and asthma.

Efficient catalytic CO2 conversion by harnessing visible-light energy is a substantial challenge for sustainability. Photocatalytic materials consisting of light absorbers and catalysts have been ...