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An unusual DNA structure may hold the key to treating one of the deadliest cancers affecting women, which claims more than ...
Researchers at Washington University School of Medicine in St. Louis have revealed the structure of a key protein involved in ...
In many cases, however, the molecular determinants of helicase specialization and the repertoire of functional helicase substrates are uncertain or were probed superficially with a few model NA ...
A series of fluorescent ligands, which were systematically constructed from thiazole orange scaffold, was investigated for their interactions with G-quadruplex structures and antitumor activity. Among ...
--Assembly Biosciences, Inc., a biotechnology company developing innovative therapeutics targeting serious viral diseases, today announced that the first participant has been dosed in the Phase 1 ...
Single-molecule fluorescence resonance energy transfer (smFRET) methods were used to study the assembly pathway and DNA unwinding activity of the bacteriophage T4 helicase–primase (primosome) complex.