A new study in the journal Nature throws a new theory into the fray. Analyzing a wealth of DNA collected from fossilized human bones, the researchers found that the first Indo-European speakers ...
Ancient DNA locates the geographic origin of Proto-Indo-Europeans and Proto-Anatolians and describes their early migrations out of the Caucasus Lower Volga and North Pontic regions of present-day ...
Learning about your genetics and ancestry is easier than ever. All you need to do is choose from the many DNA ancestry tests available online, receive your kit and send back the required DNA samples.
The G-quadruplex (G4) structure is formed specifically by DNA or RNA molecules and represents a planar structure formed by four guanine bases linked via hydrogen bonds. (1,2) This structure is ...
Homologous recombination (HR) is important for DNA damage tolerance during replication. The yeast Shu complex, a conserved homologous recombination factor, prevents replication-associated mutagenesis.
Other methods for measuring origin activation, such as generation of single-stranded DNA or incorporation of nucleoside analogs ... important to test our hypothesis that displacement of the helicase ...
To our knowledge, there are no existing investigations employing a separation protocol resembling the helicase dissociation process of DNA. Helicases break hydrogen bridges in a helicoidal-sequence ...
At the interface of repair with transcription and replication, helicase–nuclease–RPA partnerships have major roles in genome maintenance by directional unwinding and processing structured nucleic ...
Human DNA2 helicase can bind and unfold G4 structures, with this activity predicted to occur in DNA replication (Okazaki fragment processing) and telomere elongation (Masuda-Sasa et al., 2008). In ...
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