This study presents a useful finding that targeting amino acid metabolism can overcome Trastuzumab resistance in HER2+ breast cancer. The evidence supporting the claims of the authors is solid and the ...

New research has investigated the mechanism by which bivalency functions to poise genes for expression during cell differentiation, providing insight into a long-standing paradigm in the regulation of ...

Abstract Research of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Fibromyalgia (FM), two acquired chronic illnesses affecting mainly females, has failed to ascertain their frequent ...

histone modifications and targeted proteins. Longitudinal proteomics study identifies variability in proteome alterations in different tissues, reveals distinct consensus semitryptic motives in ...

A major population proteomics study using UK Biobank patient samples backed by 14 pharma companies has launched today with the promise of delivering a "transformation" in the study of diseases and ...

Sepsis is a major life-threatening syndrome of organ dysfunction caused by a dysregulated host response due to infection. Dysregulated immunometabolism is fundamental to the onset of sepsis.

Lysine residues in N-terminal tails of histone H3 are the major targets for post-translational modifications (PTMs ... Genome Sequence Archive (Genomics, Proteomics, and Bioinformatics 2021); GSA: ...

Correspondence to Dr Hyota Takamatsu, Department of Respiratory Medicine and Clinical Immunology, Graduate School of Medicine, Osaka University, Osaka 565-0871, Japan; ...