Concomitant radiotherapy plus temozolomide significantly increased progression-free survival versus radiotherapy alone in IDH ...

P53 Overexpression and mutation seen in children >3 years and young adults; possible independent prognostic factor Less common in elderly patients EGFR/EGFRvIII Less common in pediatric patients ...

An AI-driven tool enhances stereotactic radiosurgery for small brain metastases by predicting local failure risks, optimizing radiation dosing, and personalizing MRI follow-ups.

Blood does more than just carry oxygen and nutrients. Its many “markers,” known as antigens, can trigger unexpected responses. Most folks have heard about the blood groups A, B, and O, and the Rh ...

For 30 years, researchers have known that Huntington's is caused by an inherited mutation in the Huntingtin (HTT) gene, but they didn't know how the mutation causes brain cell death. A study ...

One of the earliest strains of bird flu isolated from a human in Texas shows a unique constellation of mutations that enable it to more easily replicate in human cells and cause more severe ...

Video: Broad Institute of MIT and Harvard At a glance: Study explains long-standing question of why Huntington’s disease symptoms typically do not appear until midlife even though patients are born ...

This means that the damage has multiple chances to generate harmful mutations, which can lead to cancer. While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms ...

The Garvan team revealed that this is not the case -- rather, the critical trigger is mutations in 'rogue clone' B cells. "This discovery fundamentally changes our understanding of how infections ...

Researchers have identified a novel genetic risk factor for SARS-CoV-2 infection, providing new insights into the virus’ ability to invade human cells. SARS-CoV-2 is the virus that spreads COVID-19.

Abstract 4589. Komrokji RS, Ali NHA, Xie Z, et al. IDH-1 somatic mutations are more commonly observed among patients with comcomitant myelodysplastic syndromes (MDS) and autoimmune rheumatoid ...