Insulin-like growth factor (IGF) 1 is a member of a family that is involved ... IGF1, IGF2 and insulin act primarily through tyrosine-kinase-linked receptors—the IGF1 receptor (IGF1R) and ...

As pari passu circulating insulin-like growth factor 1 (IGF-1) bioavailability progressively decreases ... by the irreversible death of highly differentiated neurons and sensory receptor cells. Among ...

TEPEZZA, as the first FDA-approved treatment for thyroid eye disease, marks a major breakthrough in managing TED, addressing a critical medical gap for patients who have long had few treatment ...

Secondary lymphedema occurs when, after surgery or radiotherapy, the lymphatic system cannot drain interstitial fluid effectively, leading to inflammation and fluid accumulation in the limbs. Previous ...

Ersodetug, a novel, fully human monoclonal antibody for the treatment of hyperinsulinism (HI), receives Breakthrough Therapy Designation and ...

Heterocyclic insulin-like growth factor 1 receptor (IGF-1R; CD221) inhibitors potentially useful for the treatment of thyroid-associated ophthalmopathy (Graves’ ophthalmopathy) have been disclosed in ...

we found that ADM2 facilitates the expression of insulin-like growth factor 2 (IGF-II), which then triggers the activation of the AKT-GSK3β-mTOR signaling pathway via the IGF-II receptor (IGF-IIR ...

The Graves Ophthalmopathy market is expected to surge due to the disease's increasing prevalence and awareness during the ...

Peptides have gained significant attention in research due to their possible role in regulating various physiological processes. Among these, Ipamorelin and Growth Hormone hormone-releasing peptide-2 ...

Laboratory tests were done at the Turku University Hospital Laboratory, except for the IGF-1 test, which was performed in the Islab-laboratory (Kuopio, Finland). Umbilical serum TSH (uS-TSH), serum ...

Three people with type 1 diabetes who received Vertex Pharma’s islet cell therapy VX-880 have been able to come off insulin altogether within a year, raising the prospect of a life without ...