In vivo, αKG supplementation and OGDH suppression both increased the number of goblet and Paneth cells and raised intestinal 5-hydroxymethylcytosine (5hmC) levels.

Appendix cancer is a rare but increasingly recognized malignancy, often discovered incidentally during surgery for presumed ...

RESULTS Cells in focal patches of gastric metaplasia contained secretory granules of both gastric and goblet cell phenotypes. MUC5AC and TFF1 were present as expected in gastric foveolar cells but in ...

The totality of bacteria, viruses and fungi that exist in and on a multicellular organism forms its natural microbiome. The ...

Research carried out on mice has revealed how a hormone released by the intestine acts on the brain and helps regulate the ...

Up to half of patients with Crohn's disease, an inflammatory bowel disease, develop a complication called fibrosis, where the ...

Mitsugumin 53 drives stem cell differentiation easing intestinal injury and inflammation Yumeng Pei Meng Fang Rui-Ping Xiao Research Open Access 11 Jun 2025 Signal Transduction and Targeted Therapy ...

During animal development, cells divide and arrange themselves in a coordinated way, eventually forming the embryo. The cells ...

Goblet cell carcinoid (GCC): A rare appendiceal tumour showing features of both neuroendocrine and adenocarcinoma cells. Appendiceal neoplasm: Any abnormal growth arising from the appendix ...

We have shown that: (1) IL-7 is constitutively produced by intestinal goblet cells; 8 (2) IL-7 transgenic mice, in which strong promoters drive systemic overexpression, develop colitis that mimics the ...

Therapeutic effects of natural products against relative diseases by targeting intestinal mucosal immunity; 5. The target immune cells or signaling pathways involved in the modulation of natural ...