The following is a summary of “Novel protein C variant p.C101F results in early intracellular degradation that drives type I ...

“Protein degradation is based on intracellular processes, and it builds on the cell's natural system for recycling unneeded or defective proteins. This disposal process, which is called the ubiquitin ...

Prof. Ciechanover discussed the history of ubiquitin and the crucial role of intracellular protein degradation in quality control, cellular processes, and differentiation. He also highlighted the ...

Unlock the secret to building muscle without lifting heavy weights using science-backed methods that maximize growth with lighter workouts.

Strong evidence for ALS often comes from familial forms of the disease, where specific gene mutations— for example in the ...

After validating its efficacy, they designed and synthesized another clozapine PROTAC targeting the estrogen receptor alpha (ERα), which was shown to induce degradation of the ERα protein in MCF-7 ...

In his talk, Prof. Ciechanover discussed the history of ubiquitin and the crucial role of intracellular protein degradation in quality control, cellular processes, and differentiation. He also ...