Every organism on Earth is a well-oiled machine in its own environment. It makes sense then that every piece of every process ...

The following is a summary of “Novel protein C variant p.C101F results in early intracellular degradation that drives type I ...

The amount of protein an individual needs depends on their age and sex. However, most adults on a 2,000-calorie diet require 50 grams (g) of protein daily. Protein is a part of every cell in the ...

The intestinal epithelium is a highly dynamic barrier that regulates digestion, absorption, immune responses, and communication between the gut microbiota and the nervous system. To maintain ...

Unsurprisingly, this is also a common worry among people that are looking to buy their first electric car. But is battery degradation in electric vehicles (EVs) fact or fiction? To find out, each year ...

Unlocking the potential of protein degradation in cancer research Donate Research and discoveries Study and careers Industry partnerships About us Support us Research and discoveries Find a researcher ...

It is observed that GSD can surpass the off-state degradation (OSD) stress mode. By separating different types of traps, we clarified the physical mechanism of GSD. Based on the understanding, a ...

Prof. Ciechanover discussed the history of ubiquitin and the crucial role of intracellular protein degradation in quality control, cellular processes, and differentiation. He also highlighted the ...

In his talk, Prof. Ciechanover discussed the history of ubiquitin and the crucial role of intracellular protein degradation in quality control, cellular processes, and differentiation. He also ...

Why Trust Us? More recently, though, a newer step worked its way into the (extremely thought-through and highly important) process of making morning brew: adding a scoop of protein powder.

After validating its efficacy, they designed and synthesized another clozapine PROTAC targeting the estrogen receptor alpha (ERα), which was shown to induce degradation of the ERα protein in MCF-7 ...