Frontiers19d
Itraconazole promotes melanoma cells apoptosis via inhibiting hedgehog signaling pathway-mediated autophagy
A375 and A2058 cells were transfected for 24 h with an adenovirus containing the mCherry-eGFP-LC3B gene (Suzhou Genepharma, China), a marker used for tracking autophagy flux. After transfection, the ...
C&EN21d
Multifunctional Artificial Peroxisome Basing on Lactate Oxidase as a Self-Cascade Enhancing Active Oxygen Amplifier for Tumor Therapy
Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou 225001, China Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and ...
Medical Xpress28d
Powering brain health: How autophagy protects neurons by controlling their glucose consumption
Get Instant Summarized Text (Gist) Autophagy, particularly through the protein ATG5, plays a crucial role in maintaining brain health by regulating glucose metabolism in neurons. In Purkinje cells ...
Cancer Research28d
An Autophagy-Targeting Chimera Induces Degradation of Androgen Receptor Mutants and AR-v7 in Castration-Resistant Prostate Cancer
1Cellular Degradation Biology Center, College of Medicine, Seoul National University, Seoul, Republic of Korea. 2Department of Biomedical Sciences, College of Medicine, Seoul National University, ...