A research team from POSTECH has developed a biodegradable polymer-based delivery system that efficiently transports mRNA.
Recent studies have explored the mechanisms by which these copolymers bind to lipid membranes ... Polymers made from two or more different monomers, which can impart unique properties compared ...
Simultaneous dissociation of ROCKET and ROCKET AAXWA leads to the ejection of unfolded monomers, which can be quantified by nMS (top row). Addition of CDL to the same mixture results in lipid binding ...
The SEC condition specified in our Standard Operating Procedure (SOP) Guidance Manual provides good separation of monomers ... including viral vectors, lipid nanoparticles, and extracellular ...
The Supporting Information is available free of charge at https://pubs.acs.org/doi/10.1021/acs.langmuir.4c04598. Additional methods describing sample preparation and ...
The hydrogel, which is mainly composed of acrylamide monomers, has the function of stabilizing dispersed proteins and nucleic acid by covalent bonds. Moreover, this hybrid construct has to support and ...
Yan, “Toxicity of cationic lipids and cationic polymers in gene delivery,” J ... Okano, “Transfection efficiency increases by incorporating hydrophobic monomer units into polymeric gene carriers,” J.
A research team has developed a biodegradable polymer-based delivery system that efficiently transports mRNA.
Lipids are a fundamental class of organic molecules implicated in a wide range of biological processes related to their structural diversity, and based on this can be broadly classified into five ...
Department of Chemistry and Biochemistry, Iona University, 715 North Avenue, New Rochelle, New York 10801, United States Artificial Cell Membrane Systems Group, Kanagawa Institute of Industrial ...