Johns Hopkins University School of Medicine researchers have discovered a dual regulatory mechanism safeguarding ...

Biologists have discovered a new type of RNA-splicing regulation that helps to determine which protein-coding exons will be included in messenger RNA transcripts.

Rett syndrome is a rare genetic disease affecting 1 in 10,000 newborn girls, characterized by sudden regression around 1 year ...

This parent-child relationship helps regulate brain regeneration and repair ... system made it possible to assess the functional activity of neural stem cells. Single cell sequencing and spatial ...

In general, chemotherapy medications work by attacking cells or by preventing them from ... they’re likely due to certain areas of the brain being triggered during treatment.

Objective Innate immunity plays important roles in pancreatic ductal adenocarcinoma (PDAC), as non-T-cell-enriched tumour. Neutrophils are major players in innate immune system. Here, we aimed to ...

Design We performed single-cell RNA sequencing and spatial transcriptomic analysis in primary colorectal cancer (CRC) and metastases in the liver (lCRC) or ovary (oCRC). We also conducted ...

memento is a Python package for estimating the mean, variability, and gene correlation from scRNA-seq data as well as contructing a framework for hypothesis testing of differences in these parameters ...

Harvard Medical School research reveals highly specialized regulatory T cells that curb inflammation and act as gatekeepers to protect the inner regions of the brain. The work, which was done in mice, ...

The designation was Sanghera’s way of emphasizing Oxford Nanopore’s commitment over the next five years to combine proteomics with multi-omics in its menu of sequencing offerings.

By using advanced imaging techniques, they have observed these changes live for the first time, deepening our understanding of brain plasticity. Our nerve cells, or neurons, communicate by sending ...