Researchers from the Bellvitge Biomedical Research Institute (IDIBELL) and the Germans Trias i Pujol Research Institute (IGTP ...

Researchers from the Bellvitge Biomedical Research Institute (IDIBELL) and the Germans Trias i Pujol Research Institute (IGTP ...

Spliceosomes act as an editing tool, helping to make sense of the fragmented messages stored in pre-mRNA ... mechanism of minor intron recognition and sheds light on the evolution of the splicing ...

A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA. Splicing is .

Recent research has shed light on the intricate mechanisms involved in mRNA recognition ... in various aspects of RNA metabolism, including splicing and export.

GMRSP regulates the glycolysis by counteracting hnRNP A2B1-mediated pyruvate kinase M pre-mRNA alternative splicing and control the phenotypic transition of VSMCs.

The mechanisms and physiological consequences of ... heart and skeletal muscle postnatal development including alternative splicing, selection of polyadenylation sites, translation, mRNA stability, ...

In human cells, only a small proportion of the information written in genes is used to produce proteins. How does the cell ...

The most commonly mutated ALS-linked genes are reviewed with an emphasis on disease-causing mechanisms ... to a region in the 3′UTR of the TARDBP pre-mRNA leading to alternative polyadenylation and ...

Background: The spliceosome plays an important role in mRNA alternative splicing and is aberrantly expressed in ... To explore the potential regulatory mechanisms of these genes, a protein-protein ...

Serpine1 mRNA-binding protein 1 (SERBP1) is a unique member of this group, being mostly disordered and lacking canonical RNA-binding domains. We defined SERBP1’s interactome, uncovered novel roles in ...