Researchers have developed a computational method to explicitly consider the impact of water while designing membrane receptors with enhanced stability and signaling, paving the way for novel drug ...

New research reveals that brain cells use a muscle-like signaling mechanism to relay information over long distances.

Engineered immune cells called CAR-T cells are used in the treatment of cancer. Researchers from Uppsala University have now ...

Researchers have identified how CBD interacts with cannabinoid receptors to mitigate the negative effects of THC, the psychoactive component of cannabis.

In this manuscript the authors established a novel three-dimensional culture system for stratified epithelia that allows epithelial cells to undergo epithelial-to-mesenchymal transition (EMT) and ...

Adhesion G protein-coupled receptors (GPCRs) are a group of cell-surface sensors associated with many body functions and diseases. However, they are not yet sufficiently understood to be exploited for ...

Olive oil bioactives, including MUFAs, polyphenols, and triterpenoids, modulate gene expression linked to insulin sensitivity ...

Innovative designs of GPCRs with enhanced signaling and stability offer new insights for drug discovery and synthetic biology ...

The FDA approved trastuzumab deruxtecan for adult patients with unresectable or metastatic HER2-low or HER2-ultralow breast ...