Weill Cornell Medicine investigators have identified in a preclinical model a specific brain circuit whose inhibition appears to reduce anxiety without side effects.

And raptin levels were much lower in those with obesity. "Raptin binds to glutamate metabotropic receptor 3 (GRM3) in neurons of the hypothalamus and stomach to inhibit appetite and gastric ...

In a study published in Cell, a research team led by Zhu Shujia from the Center for Excellence in Brain Science and ...

Although scientists can learn a lot from cell culture and animal models, they cannot truly substitute for all parts of the ...

NMDA receptors are heteromeric tetramers composed of two obligatory GluN1 and two alternative subunits, either GluN2 (N2A to N2D) or GluN3 (N3A and N3B). Over the past decade, molecular ...

Certain proteins found in the human brain have long been known to be critical to controlling how brain cells communicate with each other.

Research led by Jia Zhou in the Hibbs Lab at UC San Diego has mapped the structures of human brain receptors for the ... understand how different protein subunits can assemble in many ways.