On a molecular level ... 5d) may serve either of two purposes, in teleological terms. First, autophagy may constitute a mechanism through which the cell destined to die initiates its catabolism ...

Using advanced molecular biology and genetic tools ... future studies should focus on understanding the precise mechanisms of autophagy regulation and its therapeutic application in diverse ...

Amazingly, the molecular breakthroughs in autophagy ... to involve a directed targeting-and-sequestration mechanism. During nonspecific autophagy (see figure part a), sequestration begins with ...

A recent study has uncovered the molecular mechanisms behind osteocyte death in melanoma bone metastasis, revealing that ferroptosis—an iron-dependent form of cell death—plays a central role in the ...

This study presents a valuable finding on the alterations in the autophagic-lysosomal pathway in a Huntington's disease model. The evidence supporting the claims of the authors is solid. However, the ...

Melanoma, one of the most aggressive forms of skin cancer, often metastasizes to bones, causing severe bone loss, an increased risk of fractures, and significant pain.

Melanoma, one of the most aggressive forms of skin cancer, often metastasizes to bones, causing severe bone loss, an increased risk of fractures, and significant pain. Bone metastasis is associated ...

Doctor explains how ageing can cause cancer, but with the right prevention strategies, it can be avoided. World Cancer Day 2025: As we celebrate another year of World Cancer Day, it is essential to ...

Researchers will explore a promising approach for treating degenerative diseases by replacing damaged cells with new ones and ...

Discover how excessive alcohol consumption may accelerate Alzheimers progression New research reveals shared brain ...

Genotoxic stressors, including oxidative stress, inflammation, and environmental factors are closely intertwined processes that significantly contribute to ...