Breast cancer is one of the most common cancers among women in the United States. Thanks to decades of fundamental research, ...

The Notch Gene Accelerates Colon Carcinogenesis Date: March 24, 2009 Source: CNRS (Délégation Paris Michel-Ange) Summary: Scientists recently discovered how the Notch gene is involved in the ...

a | The Notch receptors (NOTCH1–4) are heterodimers consisting of an extracellular ligand-binding domain and an intracellular domain that mediates target gene transcription. The extracellular ...

University of Manchester researchers will reveal new ways of controlling and treating breast cancer at the National Cancer Research Institute conference in Birmingham today (Monday 1 October 2007).

UCSF scientists have discovered that a gene controlling whether blood vessels differentiate into arteries or veins during embryonic development is linked to a vascular disorder in the brain that ...

Click to share on X (Opens in new window) X Click to share on Facebook (Opens in new window) Facebook For years, scientists have been attempting to turn off Notch, a common cancer-causing gene, ...

Study links mutations in notch gene to role in B cell cancers. ScienceDaily. Retrieved April 25, 2025 from www.sciencedaily.com / releases / 2017 / 10 / 171023132017.htm.

EPFL spin-off Cellestia Biotech has just been given the regulatory go-ahead to start clinical testing a molecule it has developed to treat cancers involving mutations of the Notch gene. The ...

Mutations in the Notch gene play a big role in a variety of cancers, but that's not all Notch does, making this a particularly difficult target in the development of new cancer therapies. Now ...

The Notch gene was first discovered over 100 years ago. Since that time, researchers have slowly chipped away at understanding, on a comprehensive level, how it works.