Nuclear pore complexes are best known as the communication channels that regulate the passage of all molecules to and from a cell's nucleus. Researchers, however, have shown that some of the pores ...

This showed the scientists that circulating T cells rely on the nuclear pore protein Nup210 to sense molecular signals vital for survival. "Peripheral T cell homeostasis is achieved by careful ...

References Paper Citations D'Angelo MA, Raices M, Panowski SH, Hetzer MW. Age-dependent deterioration of nuclear pore complexes causes a loss of nuclear integrity in postmitotic cells. Cell. 2009 Jan ...

Nuclear transfer of plasmid DNA complexed to an oligolysine–RGD peptide and lipofectamine appears to be an energy-dependent process involving the nuclear pore complex, since it is inhibited at 4 ...

Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that blocking the construction of nuclear pores complexes--large channels that control the flow of materials in and out ...

Nuclear pore complexes in the nuclear membrane not only control the transport of molecules into and out of the nucleus -- they play an essential role in the survival of T cells. A new study by ...

The cargo–receptor complex docks and translocates through the pore using specific NPC interactions and is dissociated on the nuclear side after binding Ran–GTP 7, 10.

Just a month ago, two Rockefeller professors published the first complete model of a nuclear pore complex created through a combination of biochemical, spectrometry and computer-modeling techniques.

Core pore. A new model for the nuclear pore complex predicts that a membrane “coat” is scaffolded by two alternating pairs of upright proteins (yellow). These “fence posts” are predicted ...

A known membrane-remodeling complex earns a newly identified role as a quality-assurance director during the assembly of nuclear pores.

Nuclear pore complexes in the nuclear membrane not only control the transport of molecules into and out of the nucleus--they play an essential role in the survival of T cells. A new study by Sanford ...

Nuclear pore complexes in the nuclear membrane not only control the transport of molecules into and out of the nucleus—they play an essential role in the survival of T cells. A new study by ...