Frontiers3d
Sanqi Oral Solution Ameliorates Renal Ischemia/Reperfusion Injury via Reducing Apoptosis and Enhancing Autophagy: Involvement of ERK/mTOR Pathways
To our surprise, compared with the sham-operated controls, the model group displayed down-regulated autophagy, with decrease in LC3II/LC3I, striking increase of SQSTM1/p62 and mild elevation of ...
Frontiers3d
Dexmedetomidine Protects Against Septic Liver Injury by Enhancing Autophagy Through Activation of the AMPK/SIRT1 Signaling Pathway
Background: Liver injury is one of the serious complications of sepsis. Previous studies suggested that dexmedetomidine (DEX) could alleviate cecal ligation and puncture (CLP)-induced liver injury.
Nature3d
Self-eating and self-killing: crosstalk between autophagy and apoptosis
Apoptosis and autophagy constitute the two self-destructive processes by which supernumerary, damaged or aged cells and organelles are eliminated. Beyond this homeostatic function, autophagy is ...