Sigvotatug Vedotin is an ADC that targets integrin αvβ6-positive tumor cells. It has an engineered antibody that ensures high ...

New research by Sumeda Nandadasa, Ph.D., reveals how a key protein associated with Meckel-Gruber syndrome, nephronophthisis, ...

R136S, or the “Christchurch mutation,” appears to protect against Alzheimer’s disease by suppressing inflammatory signaling ...

Scientists at the University of Western Australia and the Perron Institute for Neurological and Translational Science have ...

Growth factor signalling is a cell signalling pathway that ... show that heterodimerization of the receptor tyrosine kinases PDGFRa and PDGFRb negatively affects downstream ERK1/2 signaling ...

Mapping how proteins change shape is vital but slow. Now, a new method combines AI (AlphaFold2) with experimental data to ...