Additionally, PE interfered with and attenuated the interaction between P2X7R and PIP2, displaying strong docking activity with P2X7R.Taken together, PE exhibited significant anti-myocarditis activity ...

A recent research finding adds to evidence that brain inflammation is a major driver of neurodegenerative disorders such as ...

The well-studied NF-κB signaling system is a key mediator of the inflammatory response. Large-scale sequencing studies in ...

In diseases due to exposure to toxic particles like gout, macrophages elicit separate pathways for inflammation and lysosomal ...

A new lipid-based pathway essential for memory formation has been discovered by University of Queensland researchers—a ...

New research by Sumeda Nandadasa, Ph.D., reveals how a key protein associated with Meckel-Gruber syndrome, nephronophthisis, ...

Scientists at the University of Western Australia and the Perron Institute for Neurological and Translational Science have ...

PIP2: A phospholipid that modulates the activity and sensitivity of various proteins, including IP3Rs. ... Inositol Trisphosphate Receptor Signaling and Calcium Dynamics Publication Trend.

Signaling Pathways Regulating Osteoblast Differentiation & Bone Formation . Osteoblast differentiation is predominantly regulated by Wnts, which are mammalian homologs of the Drosophila secreted ...