The EMBO Journal4d
Haploinsufficient phenotypes promote selection of PTEN and ARID1A-deficient clones in human colon
Monoallelic loss of PTEN and ARID1A is identified in normal colonic epithelium. The resulting haploinsufficient phenotypes ...
Hosted on MSN6d
Daily, Long-Term Aspirin Use Reduces Colorectal Cancer Recurrence
Adjuvant treatment with 160 mg aspirin daily for three years cuts recurrence rates in patients with colorectal cancer with ...
RAD51 biomarker could complement next-generation sequencing in personalizing prostate cancer treatment
Published in Cell Reports Medicine, results of a VHIO-led study support the feasibility of using RAD51 testing to complement ...
MedPage Today15d
Study Finds Actionable Mutations in Brain Mets of Breast Cancer Patients
In addition to this, we also assessed the prognostic values of these alterations, and specifically in the HER2-positive breast cancer brain metastasis, we observed that the presence of PIK3CA ...
icr.ac.uk22d
Researchers identify two genes responsible for tumour progression in early-stage prostate cancer
They screened for genes in samples from mice with mutations in the tumour suppressor gene Pten. The paper notes that this gene is linked to 20 per cent of primary prostate cancers and up to 40 per ...
Armed robbery in Revesby1d
RAD51 Biomarker Boosts Precision in Prostate Cancer Care
Published in Cell Reports Medicine, results of a VHIO-led study support the feasibility of using RAD51 testing to complement next-generation ...
precisionmedicineonline2h
AstraZeneca Optimistic About Phase III Camizestrant Data in 2025, Reports Strong Q4 Product Growth
If the trial is successful, the firm's complete estrogen receptor antagonist would complement its other biomarker-driven breast cancer assets.