Gain-of-function mutations in fibroblast growth factor receptor (FGFR) genes are known to cause a range of skeletal disorders ...

In the subgroup with 17p deletion or TP53 mutation, zanubrutinib outperformed others with the most favorable HR (0.52) and the highest SUCRA value of 97%.

Relay Therapeutics' financial stability is strong, but zero Q3 2024 revenue and rising net losses raise concerns. Find out ...

Gene sequencing of these D1.1 viruses has found a mutation that helps the virus copy ... helping it become a more dominant variant. A shift is a bigger change. Flu viruses have eight segments ...

However, such genomic discoveries in oncology have not translated into advances for non-cancerous disease since point mutations in a single cell would be unlikely to cause non-malignant disease. An ...

These cancers have mutations in one of two genes, FOCAD or TCC37. The finding, described today in Nature, is a new synthetic lethality — a pair of genetic changes that together kill cancer cells. The ...

Recovering South Korean shopaholic-turned-climate activist Lee So-yeon used to buy new clothes almost daily -- until a $1.50 ...

CEO says the move ‘has the potential to drive a new era of growth for Workday,’ but there are concerns about customer service during the transition. Workday said Wednesday it will lay off ...

Strategies to prevent transmission are generally available, but depend on recurrence risks, ranging from high/unpredictable for many familial mtDNA point mutations to very low for sporadic, ...

The mutant form of NFIL3 demonstrated reduced stability in vitro. The potential contribution of this mutation to arthritis susceptibility was demonstrated through a preclinical model, where ...

“To reframe a situation, we often need to look at it from a different vantage point so we can shift our thoughts about it,” he writes. “The problem is, when we are washed over by negative feelings, we ...

But a series of clinical trials have led to a major shift in medical guidance — one that could change how millions of Americans approach heart health. The findings prompted the American Heart ...