Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) is a progressive neurological disease with an ...

Replacing defective microglia can halt ALSP—a fatal neurodegenerative disease—in mice and humans, offering hope for broader brain therapies.

Microglia replacement therapy helps treat people with a rare genetic condition called ALSP, suggesting the approach could ...

Adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP) is a progressive neurological disease with an ...

The findings of two recent studies give hope that the disease could one day be reversed in humans—but experts warn that this ...

Nerves look blue in the reconstructed view of a genetically engineered mouse (left) whose neurons produce a fluorescent ...

After nearly 15 years' research, scientists at the UdeM-affiliated CHU Sainte-Justine have developed a compound that has ...

Traumatic brain injury (TBI) is accompanied by the overload of reactive oxygen species (ROS), which can result in secondary brain injury. Although procyanidins (PCs) have a powerful free radical ...

World First: Mice With 2 Dads Father Their Own Offspring The two mice were normal in size, weight, and appearance, and crucially, they were fertile.