CRISPR SNP-Chip can detect and quantify single point mutation directly from unamplified whole genomic DNA samples without laborious sample preparation or optical instruments.

Nature Methods - Primer-site SNPs mask mutations. Skip to main content. Thank you for visiting nature.com. ... While testing our SNP-discovery program POLYBAYES 5 on this data set, ...

Scientists have developed a chip that can detect a type of genetic mutation known as a single nucleotide polymorphism (SNP) and send the results in real time to an electronic device. The chip is ...

Patients were assessed for the presence of the intron 6 SNP as well as a number of other mutations related to liver enzymes. Among those taking the three relevant statins, 22 were carriers of the ...

In fact, SNP-Chip stands to enable easy and point-of-care electronic screening for a wide range of genetically driven health issues, since SNPs make up 50 percent of mutations known to cause ...

Chemistry researchers have found the key to a SNP (single nucleotide polymorphism) - a natural mutation in humans - which offers protection against cardiovascular disease, and could enable drug ...

A tiny gene mutation in human liver cells could one day influence how high or low a dose patients need of about half of the clinically used drugs on the market, new research suggests. Scientists ...

The mutation induced the substitution of cytosine for thymidine (c.2161T) in exon 18 of MYH6 at nucleotide position 22,936,019. In the alpha-myosin protein, this mutation substitutes arginine to ...

While studies of SNP mutations have not offered many clues to neurodevelopment and neuropsychiatric disorders, Cantor said research into CNVs has been more fruitful.

It turns out that the type, how frequent, and where new mutations occur in the human genome depends on which DNA building blocks are nearby, found researchers from the Perelman School of Medicine ...

A tiny gene mutation in human liver cells could one day influence how high or low a dose patients need of about half of the clinically used drugs on the market, new research suggests.